Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition

Coronary microvascular disease (CMD) caused by obesity and diabetes is major contributor to heart failure with preserved ejection fraction; however, the mechanisms underlying CMD are not well understood. Using cardiac magnetic resonance applied to mice fed a high-fat, high-sucrose diet as a model of...

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Detalles Bibliográficos
Autores principales: Shah, Soham A., Reagan, Claire E., Bresticker, Julia E., Wolpe, Abigail G., Good, Miranda E., Macal, Edgar H., Billcheck, Helen O., Bradley, Leigh A., French, Brent A., Isakson, Brant E., Wolf, Matthew J., Epstein, Frederick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264569/
https://www.ncbi.nlm.nih.gov/pubmed/37325396
http://dx.doi.org/10.1016/j.jacbts.2022.11.005

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