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Thymoquinone affects the gemcitabine sensitivity of pancreatic cancer by regulating collagen via hypoxia inducible factor-1α

Objective: To clarify the potential therapeutic effects of thymoquinone (TQ) on pancreatic cancer and its gemcitabine (GEM) sensitivity. Methods: The expression levels of hypoxia inducible factor-1α (HIF-1α), collagens (COL1A1, COL3A1, and COL5A1), and transforming growth factor-β1 (TGFβ1) in pancre...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhanxue, Liu, Linxun, Chen, Hekai, Li, Shuai, Guo, Yan, Hou, Xiaofan, Yang, Jinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264578/ https://www.ncbi.nlm.nih.gov/pubmed/37324458 http://dx.doi.org/10.3389/fphar.2023.1138265

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