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The multikinase inhibitor axitinib in the treatment of advanced hepatocellular carcinoma: the current clinical applications and the molecular mechanisms
Advanced hepatocellular carcinoma (HCC) is a formidable public health problem with limited curable treatment options. Axitinib, an oral tyrosine kinase inhibitor, is a potent and selective second-generation inhibitor of vascular endothelial growth factor receptor (VEGFR) 1, 2, and 3. This anti-angio...
Autores principales: | Jiang, Hao, Liao, Jian, Wang, Liezhi, Jin, Chong, Mo, Jinggang, Xiang, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264605/ https://www.ncbi.nlm.nih.gov/pubmed/37325670 http://dx.doi.org/10.3389/fimmu.2023.1163967 |
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