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Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017

BACKGROUND: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, which poses huge disease burdens in China. A study was conducted to systematically analyze the recent prevalence trend of AF and age-related disparities in AF risk among the nationwide healthy check-up population. METHOD:...

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Autores principales: Sun, Tao, Ye, Mao, Lei, Fang, Qin, Juan-Juan, Liu, Ye-Mao, Chen, Ze, Chen, Ming-Ming, Yang, Chengzhang, Zhang, Peng, Ji, Yan-Xiao, Zhang, Xiao-Jing, She, Zhi-Gang, Cai, Jingjing, Jin, Zhao-Xia, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264614/
https://www.ncbi.nlm.nih.gov/pubmed/37324618
http://dx.doi.org/10.3389/fcvm.2023.1151575
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author Sun, Tao
Ye, Mao
Lei, Fang
Qin, Juan-Juan
Liu, Ye-Mao
Chen, Ze
Chen, Ming-Ming
Yang, Chengzhang
Zhang, Peng
Ji, Yan-Xiao
Zhang, Xiao-Jing
She, Zhi-Gang
Cai, Jingjing
Jin, Zhao-Xia
Li, Hongliang
author_facet Sun, Tao
Ye, Mao
Lei, Fang
Qin, Juan-Juan
Liu, Ye-Mao
Chen, Ze
Chen, Ming-Ming
Yang, Chengzhang
Zhang, Peng
Ji, Yan-Xiao
Zhang, Xiao-Jing
She, Zhi-Gang
Cai, Jingjing
Jin, Zhao-Xia
Li, Hongliang
author_sort Sun, Tao
collection PubMed
description BACKGROUND: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, which poses huge disease burdens in China. A study was conducted to systematically analyze the recent prevalence trend of AF and age-related disparities in AF risk among the nationwide healthy check-up population. METHOD: We conducted a nationwide cross-sectional study involving 3,049,178 individuals ≥35 years from health check-up centers to explore the prevalence and trend of AF by age, sex, and region from 2012 to 2017. Additionally, we analyzed risk factors associated with AF among the overall population and different age groups via the Boruta algorithm, the LASSO regression, and the Logistic regression. RESULT: The age-, sex-. and regional-standardized prevalence of AF kept stable between 0.4%–0.45% among national physical examination individuals from 2012 to 2017. However, the prevalence of AF showed an undesirable upward trend in the 35–44-year age group (annual percentage changes (APC): 15.16 [95%CI: 6.42,24.62]). With increasing age, the risk of AF associated with the overweight or obesity gradually exceeds that associated with diabetes and hypertension. In addition to traditional leading risk factors such as age≥65 and coronary heart disease, elevated uric acid and impaired renal function were tightly correlated with AF in the population. CONCLUSION: The significant rise in the prevalence of AF in the 35–44 age group reminds us that in addition to the elderly (the high-risk group), younger people seem to be in more urgent need of attention. Age-related disparities in AF risk also exist. This updated information may provide references for the national prevention and control of AF.
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spelling pubmed-102646142023-06-15 Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017 Sun, Tao Ye, Mao Lei, Fang Qin, Juan-Juan Liu, Ye-Mao Chen, Ze Chen, Ming-Ming Yang, Chengzhang Zhang, Peng Ji, Yan-Xiao Zhang, Xiao-Jing She, Zhi-Gang Cai, Jingjing Jin, Zhao-Xia Li, Hongliang Front Cardiovasc Med Cardiovascular Medicine BACKGROUND: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, which poses huge disease burdens in China. A study was conducted to systematically analyze the recent prevalence trend of AF and age-related disparities in AF risk among the nationwide healthy check-up population. METHOD: We conducted a nationwide cross-sectional study involving 3,049,178 individuals ≥35 years from health check-up centers to explore the prevalence and trend of AF by age, sex, and region from 2012 to 2017. Additionally, we analyzed risk factors associated with AF among the overall population and different age groups via the Boruta algorithm, the LASSO regression, and the Logistic regression. RESULT: The age-, sex-. and regional-standardized prevalence of AF kept stable between 0.4%–0.45% among national physical examination individuals from 2012 to 2017. However, the prevalence of AF showed an undesirable upward trend in the 35–44-year age group (annual percentage changes (APC): 15.16 [95%CI: 6.42,24.62]). With increasing age, the risk of AF associated with the overweight or obesity gradually exceeds that associated with diabetes and hypertension. In addition to traditional leading risk factors such as age≥65 and coronary heart disease, elevated uric acid and impaired renal function were tightly correlated with AF in the population. CONCLUSION: The significant rise in the prevalence of AF in the 35–44 age group reminds us that in addition to the elderly (the high-risk group), younger people seem to be in more urgent need of attention. Age-related disparities in AF risk also exist. This updated information may provide references for the national prevention and control of AF. Frontiers Media S.A. 2023-05-31 /pmc/articles/PMC10264614/ /pubmed/37324618 http://dx.doi.org/10.3389/fcvm.2023.1151575 Text en © 2023 Sun, Ye, Lei, Qin, Liu, Chen, Chen, Yang, Zhang, Ji, Zhang, She, Cai, Jin and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Sun, Tao
Ye, Mao
Lei, Fang
Qin, Juan-Juan
Liu, Ye-Mao
Chen, Ze
Chen, Ming-Ming
Yang, Chengzhang
Zhang, Peng
Ji, Yan-Xiao
Zhang, Xiao-Jing
She, Zhi-Gang
Cai, Jingjing
Jin, Zhao-Xia
Li, Hongliang
Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title_full Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title_fullStr Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title_full_unstemmed Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title_short Prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in China, 2012–2017
title_sort prevalence and trend of atrial fibrillation and its associated risk factors among the population from nationwide health check-up centers in china, 2012–2017
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264614/
https://www.ncbi.nlm.nih.gov/pubmed/37324618
http://dx.doi.org/10.3389/fcvm.2023.1151575
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