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Radiation therapy for prostate cancer in Syrian refugees: facing the need for change
PURPOSE: To report the utilization of radiation therapy in Syrian refugee patients with prostate cancer residing in Turkey. METHODS AND MATERIALS: A multi-institutional retrospective review including 14 cancer centers in Turkey was conducted to include 137 Syrian refugee patients with prostate cance...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264678/ https://www.ncbi.nlm.nih.gov/pubmed/37325331 http://dx.doi.org/10.3389/fpubh.2023.1172864 |
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author | Eren, Mehmet Fuat Kilic, Sarah S. Eren, Ayfer Ay Kaplan, Sedenay Oskeroglu Teke, Fatma Kutuk, Tugce Bicakci, Beyhan Ceylaner Hathout, Lara Moningi, Shalini Orio, Peter Atalar, Banu Sayan, Mutlay |
author_facet | Eren, Mehmet Fuat Kilic, Sarah S. Eren, Ayfer Ay Kaplan, Sedenay Oskeroglu Teke, Fatma Kutuk, Tugce Bicakci, Beyhan Ceylaner Hathout, Lara Moningi, Shalini Orio, Peter Atalar, Banu Sayan, Mutlay |
author_sort | Eren, Mehmet Fuat |
collection | PubMed |
description | PURPOSE: To report the utilization of radiation therapy in Syrian refugee patients with prostate cancer residing in Turkey. METHODS AND MATERIALS: A multi-institutional retrospective review including 14 cancer centers in Turkey was conducted to include 137 Syrian refugee patients with prostate cancer treated with radiation therapy (RT). Toxicity data was scored using the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0. Noncompliance was defined as a patient missing two or more scheduled RT appointments. RESULTS: Advanced disease, defined as stage III or IV, was reported in 64.2% of patients while androgen deprivation therapy (ADT) was only administrated to 20% of patients. Conventionally fractionated RT with a median number of 44 fractions was delivered to all patients with curative intent (n = 61) while palliative RT (n = 76) was delivered with a median number of 10 fractions. The acute grade 3–4 toxicity rate for the entire cohort was 16%. Noncompliance rate was 42%. CONCLUSION: Most Syrian refugee prostate cancer patients presented with advanced disease however ADT was seldom used. Despite the low treatment compliance rate, conventional fractionation was used in all patients. Interventions are critically needed to improve screening and increase the use of standard-of-care treatment paradigms, including hypofractionated RT and ADT. |
format | Online Article Text |
id | pubmed-10264678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102646782023-06-15 Radiation therapy for prostate cancer in Syrian refugees: facing the need for change Eren, Mehmet Fuat Kilic, Sarah S. Eren, Ayfer Ay Kaplan, Sedenay Oskeroglu Teke, Fatma Kutuk, Tugce Bicakci, Beyhan Ceylaner Hathout, Lara Moningi, Shalini Orio, Peter Atalar, Banu Sayan, Mutlay Front Public Health Public Health PURPOSE: To report the utilization of radiation therapy in Syrian refugee patients with prostate cancer residing in Turkey. METHODS AND MATERIALS: A multi-institutional retrospective review including 14 cancer centers in Turkey was conducted to include 137 Syrian refugee patients with prostate cancer treated with radiation therapy (RT). Toxicity data was scored using the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0. Noncompliance was defined as a patient missing two or more scheduled RT appointments. RESULTS: Advanced disease, defined as stage III or IV, was reported in 64.2% of patients while androgen deprivation therapy (ADT) was only administrated to 20% of patients. Conventionally fractionated RT with a median number of 44 fractions was delivered to all patients with curative intent (n = 61) while palliative RT (n = 76) was delivered with a median number of 10 fractions. The acute grade 3–4 toxicity rate for the entire cohort was 16%. Noncompliance rate was 42%. CONCLUSION: Most Syrian refugee prostate cancer patients presented with advanced disease however ADT was seldom used. Despite the low treatment compliance rate, conventional fractionation was used in all patients. Interventions are critically needed to improve screening and increase the use of standard-of-care treatment paradigms, including hypofractionated RT and ADT. Frontiers Media S.A. 2023-05-31 /pmc/articles/PMC10264678/ /pubmed/37325331 http://dx.doi.org/10.3389/fpubh.2023.1172864 Text en Copyright © 2023 Eren, Kilic, Eren, Kaplan, Teke, Kutuk, Bicakci, Hathout, Moningi, Orio, Atalar and Sayan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Public Health Eren, Mehmet Fuat Kilic, Sarah S. Eren, Ayfer Ay Kaplan, Sedenay Oskeroglu Teke, Fatma Kutuk, Tugce Bicakci, Beyhan Ceylaner Hathout, Lara Moningi, Shalini Orio, Peter Atalar, Banu Sayan, Mutlay Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title | Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title_full | Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title_fullStr | Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title_full_unstemmed | Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title_short | Radiation therapy for prostate cancer in Syrian refugees: facing the need for change |
title_sort | radiation therapy for prostate cancer in syrian refugees: facing the need for change |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264678/ https://www.ncbi.nlm.nih.gov/pubmed/37325331 http://dx.doi.org/10.3389/fpubh.2023.1172864 |
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