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Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population

Primary biliary cholangitis (PBC) is a rare autoimmune disease with a clear predisposition for human leukocyte antigen (HLA)-DR/DQ-associated loss of immune tolerance for the E2 component of the pyruvate dehydrogenase complex. Three-field-resolution HLA imputation of 1,670 Japanese PBC patients and...

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Detalles Bibliográficos
Autores principales:	Khor, Seik-Soon, Ueno, Kazuko, Nishida, Nao, Kawashima, Minae, Kawai, Yosuke, Aiba, Yoshihiro, Hitomi, Yuki, Nagasaki, Masao, Nakamura, Minoru, Tokunaga, Katsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264690/ https://www.ncbi.nlm.nih.gov/pubmed/37325616 http://dx.doi.org/10.3389/fimmu.2023.1151502

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