Cargando…

Keratinocytes use FPR2 to detect Staphylococcus aureus and initiate antimicrobial skin defense

INTRODUCTION: Keratinocytes form a multilayer barrier that protects the skin from invaders or injuries. The barrier function of keratinocytes is in part mediated by the production of inflammatory modulators that promote immune responses and wound healing. Skin commensals and pathogens such as Staphy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lebtig, Marco, Scheurer, Jasmin, Muenkel, Marie, Becker, Janna, Bastounis, Effie, Peschel, Andreas, Kretschmer, Dorothee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264695/ https://www.ncbi.nlm.nih.gov/pubmed/37325619 http://dx.doi.org/10.3389/fimmu.2023.1188555

Ejemplares similares

Staphylococcus aureus Depends on Eap Proteins for Preventing Degradation of Its Phenol-Soluble Modulin Toxins by Neutrophil Serine Proteases
por: Kretschmer, Dorothee, et al.
Publicado: (2021)

Inhibition of the ATP synthase sensitizes Staphylococcus aureus towards human antimicrobial peptides
por: Liu, Liping, et al.
Publicado: (2020)

The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus
por: Schlatterer, Katja, et al.
Publicado: (2018)

The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses
por: Kraus, Dirk, et al.
Publicado: (2008)

Spatiotemporal characterization of endothelial cell motility and physical forces during exposure to Borrelia burgdorferi
por: Muenkel, Marie, et al.
Publicado: (2022)

Staphylococcus aureus Internalized by Skin Keratinocytes Evade Antibiotic Killing
por: Al Kindi, Arwa, et al.
Publicado: (2019)

A Stiff Extracellular Matrix Favors the Mechanical Cell Competition that Leads to Extrusion of Bacterially-Infected Epithelial Cells
por: Aparicio-Yuste, Raúl, et al.
Publicado: (2022)

Staphylococcus aureus Releases Proinflammatory Membrane Vesicles To Resist Antimicrobial Fatty Acids
por: Kengmo Tchoupa, Arnaud, et al.
Publicado: (2020)

Methicillin-Resistant Staphylococcus aureus Adaptation to Human Keratinocytes
por: Soong, Grace, et al.
Publicado: (2015)

FPR Ligands
por: Liu, Ying, et al.
Publicado: (2013)

Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection
por: Dokoshi, Tatsuya, et al.
Publicado: (2020)

Functional characteristics of the Staphylococcus aureus δ-toxin allelic variant G10S
por: Cheung, Gordon Y. C., et al.
Publicado: (2015)

Staphylococcus aureus Activates the Aryl Hydrocarbon Receptor in Human Keratinocytes
por: Stange, Eva-Lena, et al.
Publicado: (2022)

SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense
por: Klopfenstein, Nathan, et al.
Publicado: (2021)

Borrelia burgdorferi modulates the physical forces and immunity signaling in endothelial cells
por: Yuste, Raúl Aparicio, et al.
Publicado: (2022)

Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin
por: Krueger, Annika, et al.
Publicado: (2022)

Cutaneous Immune Defenses Against Staphylococcus aureus Infections
por: Choi, Ji Hae, et al.
Publicado: (2014)

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
por: Zhuang, Youwen, et al.
Publicado: (2022)

Neutrophils in innate host defense against Staphylococcus aureus infections
por: Rigby, Kevin M., et al.
Publicado: (2011)

Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes
por: Wu, Xia, et al.
Publicado: (2021)

Protein A Modulates Neutrophil and Keratinocyte Signaling and Survival in Response to Staphylococcus aureus
por: Ledo, Camila, et al.
Publicado: (2021)

Antimicrobial Treatment of Staphylococcus aureus Biofilms
por: Tuon, Felipe Francisco, et al.
Publicado: (2023)

Publishing protocols as a new PI
por: Bastounis, Effie, et al.
Publicado: (2023)

Skin Infections Caused by Staphylococcus aureus
por: DEL GIUDICE, Pascal
Publicado: (2020)

Molecular Profiling of Keratinocyte Skin Tumors Links Staphylococcus aureus Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma
por: Madhusudhan, Nandhitha, et al.
Publicado: (2020)

Staphylococcus xylosus and Staphylococcus aureus as commensals and pathogens on murine skin
por: Battaglia, Michael, et al.
Publicado: (2023)

Staphylococcus aureus induces COX-2-dependent proliferation and malignant transformation in oral keratinocytes
por: Wang, Yuxia, et al.
Publicado: (2019)

Peptides from Tetraspanin CD9 Are Potent Inhibitors of Staphylococcus Aureus Adherence to Keratinocytes
por: Ventress, Jennifer K., et al.
Publicado: (2016)

Inflammatory Response Against Staphylococcus aureus via Intracellular Sensing of Nucleic Acids in Keratinocytes
por: Ngo, Quang Vinh, et al.
Publicado: (2022)

Mannitol Utilisation is Required for Protection of Staphylococcus aureus from Human Skin Antimicrobial Fatty Acids
por: Kenny, John G., et al.
Publicado: (2013)

Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2–Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages
por: Marutani, Takayuki, et al.
Publicado: (2021)

Short-Chain Fatty Acid and FFAR2 Activation – A New Option for Treating Infections?
por: Schlatterer, Katja, et al.
Publicado: (2021)

Innate Antimicrobial Defense of Skin and Oral Mucosa
por: Wertz, Philip W., et al.
Publicado: (2020)

Staphylococcus aureus – antimicrobial resistance and the immunocompromised child
por: McNeil, J Chase
Publicado: (2014)

Antimicrobial resistance in methicillin-resistant staphylococcus aureus
por: Ali Alghamdi, Bandar, et al.
Publicado: (2023)

Staphylococcus aureus Infection: Pathogenesis and Antimicrobial Resistance
por: Gherardi, Giovanni
Publicado: (2023)

Methicillin-resistant Staphylococcus aureus Skin Infections
por: Ma, Jui-Shan
Publicado: (2005)

The effect of skin fatty acids on Staphylococcus aureus
por: Neumann, Yvonne, et al.
Publicado: (2014)

Phevalin (aureusimine B)Production by Staphylococcus aureus Biofilm and Impacts on Human Keratinocyte Gene Expression
por: Secor, Patrick R., et al.
Publicado: (2012)

Early effects of Staphylococcus aureus biofilm secreted products on inflammatory responses of human epithelial keratinocytes
por: Tankersley, Amy, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vm7uadulhap21jutsn3004j9bq