A perfused multi-well bioreactor platform to assess tumor organoid response to a chemotherapeutic gradient

There is an urgent need to develop new therapies for colorectal cancer that has metastasized to the liver and, more fundamentally, to develop improved preclinical platforms of colorectal cancer liver metastases (CRCLM) to screen therapies for efficacy. To this end, we developed a multi-well perfusab...

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Detalles Bibliográficos
Autores principales: Wasson, Elisa Marie, He, Wei, Ahlquist, Jesse, Hynes, William Fredrick, Triplett, Michael Gregory, Hinckley, Aubree, Karelehto, Eveliina, Gray-Sherr, Delaney Ruth, Friedman, Caleb Fisher, Robertson, Claire, Shusteff, Maxim, Warren, Robert, Coleman, Matthew A., Moya, Monica Lizet, Wheeler, Elizabeth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264793/
https://www.ncbi.nlm.nih.gov/pubmed/37324446
http://dx.doi.org/10.3389/fbioe.2023.1193430

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