Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report

Glioblastoma multiforme (IDH wild type) is an aggressive glial tumor of astrocytic origin (WHO-grade 4) with a two-year median survival period. Patients who live more than three years are considered as long survivors. In this study, we present a long survivor of a known case of neurofibromatosis typ...

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Autores principales: Al-romaihi, Noora, Awadh, Mohammed, Albalooshi, Mohammed, Ahmed, Mohammed, Darwish, Abdulla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264866/
https://www.ncbi.nlm.nih.gov/pubmed/37323350
http://dx.doi.org/10.7759/cureus.39014
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author Al-romaihi, Noora
Awadh, Mohammed
Albalooshi, Mohammed
Ahmed, Mohammed
Darwish, Abdulla
author_facet Al-romaihi, Noora
Awadh, Mohammed
Albalooshi, Mohammed
Ahmed, Mohammed
Darwish, Abdulla
author_sort Al-romaihi, Noora
collection PubMed
description Glioblastoma multiforme (IDH wild type) is an aggressive glial tumor of astrocytic origin (WHO-grade 4) with a two-year median survival period. Patients who live more than three years are considered as long survivors. In this study, we present a long survivor of a known case of neurofibromatosis type 1 who developed GBM of the giant cell type at age 14 years, and now the patient, at age 28, has been cancer-free for more than 14 years.
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spelling pubmed-102648662023-06-15 Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report Al-romaihi, Noora Awadh, Mohammed Albalooshi, Mohammed Ahmed, Mohammed Darwish, Abdulla Cureus Pathology Glioblastoma multiforme (IDH wild type) is an aggressive glial tumor of astrocytic origin (WHO-grade 4) with a two-year median survival period. Patients who live more than three years are considered as long survivors. In this study, we present a long survivor of a known case of neurofibromatosis type 1 who developed GBM of the giant cell type at age 14 years, and now the patient, at age 28, has been cancer-free for more than 14 years. Cureus 2023-05-14 /pmc/articles/PMC10264866/ /pubmed/37323350 http://dx.doi.org/10.7759/cureus.39014 Text en Copyright © 2023, Al-romaihi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Al-romaihi, Noora
Awadh, Mohammed
Albalooshi, Mohammed
Ahmed, Mohammed
Darwish, Abdulla
Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title_full Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title_fullStr Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title_full_unstemmed Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title_short Clinicopathological and Immunohistochemistry Study of a Long Survivor of Giant Cell Glioblastoma in a Patient With Neurofibromatosis 1: Case Report
title_sort clinicopathological and immunohistochemistry study of a long survivor of giant cell glioblastoma in a patient with neurofibromatosis 1: case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264866/
https://www.ncbi.nlm.nih.gov/pubmed/37323350
http://dx.doi.org/10.7759/cureus.39014
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