Relative bioavailability and food effect study of an oral suspension of alectinib in healthy volunteers using venipuncture and capillary microsampling

Alectinib, approved as 150 mg capsules for the treatment of adults with advanced ALK‐positive non‐small cell lung cancer, is being assessed in children with ALK‐positive solid and central nervous system tumors. An ad hoc pediatric‐friendly suspension of alectinib, prepared from capsule contents, is...

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Detalles Bibliográficos
Autores principales: Liu, Stephanie N., Agarwal, Priya, Heinig, Katja, Datye, Asim, Sturm‐Pellanda, Carolina, Crugnola, Andrea, Arca, Marc, Miles, Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264912/
https://www.ncbi.nlm.nih.gov/pubmed/36978270
http://dx.doi.org/10.1111/cts.13515

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