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Does ethnicity impact CYP2D6 genotype–phenotype relationships?

Polymorphism of the CYP2D6 gene leads to substantial interindividual variability in CYP2D6 enzyme activity. Despite improvements in prediction of CYP2D6 activity based on genotype information, large interindividual variability within CYP2D6 genotypes remains and ethnicity could be a contributing fac...

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Detalles Bibliográficos
Autores principales:	Frederiksen, Trine, Areberg, Johan, Schmidt, Ellen, Stage, Tore Bjerregaard, Brøsen, Kim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264946/ https://www.ncbi.nlm.nih.gov/pubmed/36869607 http://dx.doi.org/10.1111/cts.13506

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