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Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”

Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof‐of‐concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy...

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Detalles Bibliográficos
Autores principales: Dolivo, David M., Rodrigues, Adrian E., Mustoe, Thomas A., Galiano, Robert D., Hong, Seok Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265036/
https://www.ncbi.nlm.nih.gov/pubmed/36932884
http://dx.doi.org/10.1002/advs.202207396
Descripción
Sumario:Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof‐of‐concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy of optimizing cell sources and activation stimuli to treat other types of fibrosis. [Image: see text]