Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”

Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof‐of‐concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy...

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Autores principales: Dolivo, David M., Rodrigues, Adrian E., Mustoe, Thomas A., Galiano, Robert D., Hong, Seok Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Comments
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265036/
https://www.ncbi.nlm.nih.gov/pubmed/36932884
http://dx.doi.org/10.1002/advs.202207396
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author Dolivo, David M.
Rodrigues, Adrian E.
Mustoe, Thomas A.
Galiano, Robert D.
Hong, Seok Jong
author_facet Dolivo, David M.
Rodrigues, Adrian E.
Mustoe, Thomas A.
Galiano, Robert D.
Hong, Seok Jong
author_sort Dolivo, David M.
collection PubMed
description Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof‐of‐concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy of optimizing cell sources and activation stimuli to treat other types of fibrosis. [Image: see text]
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spelling pubmed-102650362023-06-15 Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis” Dolivo, David M. Rodrigues, Adrian E. Mustoe, Thomas A. Galiano, Robert D. Hong, Seok Jong Adv Sci (Weinh) Comments Cellular therapies show promise for treatment of fibrosis. A recent article presents a strategy and proof‐of‐concept for delivering stimulated cells to degrade hepatic collagen in vivo. A discussion is presented surrounding the strengths of this approach and the potential to generalize this strategy of optimizing cell sources and activation stimuli to treat other types of fibrosis. [Image: see text] John Wiley and Sons Inc. 2023-03-18 /pmc/articles/PMC10265036/ /pubmed/36932884 http://dx.doi.org/10.1002/advs.202207396 Text en © 2023 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Comments
Dolivo, David M.
Rodrigues, Adrian E.
Mustoe, Thomas A.
Galiano, Robert D.
Hong, Seok Jong
Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title_full Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title_fullStr Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title_full_unstemmed Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title_short Comment on “Scar‐Degrading Endothelial Cells as a Treatment for Advanced Liver Fibrosis”
title_sort comment on “scar‐degrading endothelial cells as a treatment for advanced liver fibrosis”
topic Comments
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265036/
https://www.ncbi.nlm.nih.gov/pubmed/36932884
http://dx.doi.org/10.1002/advs.202207396
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