The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis (Adv. Sci. 17/2023)

Embryonic Hematopoiesis In article number 2205345, Fudi Wang, Junxia Min, and co‐workers identify and demonstrate indispensable function of zinc transporter SLC39A10 (ZIP10) and its mediated zinc homeostasis for maintaining the survival of fetal hematopoietic stem/progenitor cells. As the most impor...

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Detalles Bibliográficos
Autores principales: He, Xuyan, Ge, Chaodong, Xia, Jun, Xia, Zhidan, Zhao, Lu, Huang, Sicong, Wang, Rong, Pan, Jianwei, Cheng, Tao, Xu, Peng‐Fei, Wang, Fudi, Min, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265091/
http://dx.doi.org/10.1002/advs.202370107
Descripción
Sumario:Embryonic Hematopoiesis In article number 2205345, Fudi Wang, Junxia Min, and co‐workers identify and demonstrate indispensable function of zinc transporter SLC39A10 (ZIP10) and its mediated zinc homeostasis for maintaining the survival of fetal hematopoietic stem/progenitor cells. As the most important zinc importer on the cell membrane of hematopoietic stem cells, ZIP10 functions as a gatekeeper (like a vacuum to transport zinc across a cell membrane) for orchestrating zinc acquisition and the fate of stem cells. [Image: see text]

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