Tumor‐Associated Macrophage‐Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC‐I Expression

Tumor‐associated macrophage (TAM) infiltration facilitates glioma malignancy, but the underlying mechanisms remain unclear. Herein, it is reported that TAMs secrete exosomal LINC01232 to induce tumor immune escape. Mechanistically, LINC01232 is found to directly bind E2F2 and promote E2F2 entry into...

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Detalles Bibliográficos
Autores principales: Li, Junjun, Wang, Keshan, Yang, Chao, Zhu, Kai, Jiang, Cheng, Wang, Minjie, Zhou, Zijie, Tang, Nan, Wang, Qiangping, Wang, Siqi, Shu, Pengwei, Yuan, Hongliang, Xiong, Zhiyong, Li, Jinsong, Liang, Tao, Rao, Jin, Wang, Xuan, Jiang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265094/
https://www.ncbi.nlm.nih.gov/pubmed/37097629
http://dx.doi.org/10.1002/advs.202207067

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