BiTE‐Secreting CAR‐γδT as a Dual Targeting Strategy for the Treatment of Solid Tumors

HLA‐G is considered as an immune checkpoint protein and a tumor‐associated antigen. In the previous work, it is reported that CAR‐NK targeting of HLA‐G can be used to treat certain solid tumors. However, the frequent co‐expression of PD‐L1 and HLA‐G) and up‐regulation of PD‐L1 after adoptive immunot...

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Detalles Bibliográficos
Autores principales: Huang, Shi‐Wei, Pan, Chih‐Ming, Lin, Yu‐Chuan, Chen, Mei‐Chih, Chen, Yeh, Jan, Chia‐Ing, Wu, Chung‐Chun, Lin, Fang‐Yu, Wang, Sin‐Ting, Lin, Chen‐Yu, Lin, Pei‐Ying, Huang, Wei‐Hsaing, Chiang, Yu‐Ting, Tsai, Wan‐Chen, Chiu, Ya‐Hsu, Lin, Ting‐Hsun, Chiu, Shao‐Chih, Cho, Der‐Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265101/
https://www.ncbi.nlm.nih.gov/pubmed/37078788
http://dx.doi.org/10.1002/advs.202206856

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