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Adiponectin reverses β‐Cell damage and impaired insulin secretion induced by obesity
Obesity significantly decreases life expectancy and increases the incidence of age‐related dysfunctions, including β‐cell dysregulation leading to inadequate insulin secretion. Here, we show that diluted plasma from obese human donors acutely impairs β‐cell integrity and insulin secretion relative t...
Autores principales: | Munhoz, Ana Cláudia, Serna, Julian D. C., Vilas‐Boas, Eloisa Aparecida, Caldeira da Silva, Camille C., Santos, Tiago G., Mosele, Francielle C., Felisbino, Sergio L., Martins, Vilma Regina, Kowaltowski, Alicia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265168/ https://www.ncbi.nlm.nih.gov/pubmed/37060190 http://dx.doi.org/10.1111/acel.13827 |
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