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Chemotherapy and Immune Checkpoint Inhibitors in a Case of SMARCA4-dUT: A Case Report and Review of Literature

SMARCA4-deficient undifferentiated tumors (SMARCA4-dUT) are infrequently occurring aggressive neoplasms found predominantly in young male smokers. These tumors are distinguished by the loss of expression of Brahma-related gene 1 (BRG1) due to a deactivating mutation of SMARCA4. Immunophenotype can b...

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Detalles Bibliográficos
Autores principales: Pokhrel, Akriti, Yadav, Ruchi, Manvar, Kapil Kumar, Wu, Richard, Jaswani, Vijay, Wasserman, Carrie Brooke, Wang, Jen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265368/
https://www.ncbi.nlm.nih.gov/pubmed/37269109
http://dx.doi.org/10.1177/23247096231176220