Cargando…

Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study

BACKGROUND: Percent fluid overload greater than 5% is associated with increased mortality. The appropriate time for fluid deresuscitation depends on the patient's radiological and clinical findings. This study aimed to assess the applicability of percent fluid overload calculations for evaluati...

Descripción completa

Detalles Bibliográficos
Autores principales: Alharbi, Reham A., Aldardeer, Namareq F., Heaphy, Emily L. G., Alabbasi, Ahmad H., Albuqami, Amjad M., Hawa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Critical Care Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265412/
https://www.ncbi.nlm.nih.gov/pubmed/37313667
http://dx.doi.org/10.4266/acc.2022.01550
_version_ 1785058525472358400
author Alharbi, Reham A.
Aldardeer, Namareq F.
Heaphy, Emily L. G.
Alabbasi, Ahmad H.
Albuqami, Amjad M.
Hawa, Hassan
author_facet Alharbi, Reham A.
Aldardeer, Namareq F.
Heaphy, Emily L. G.
Alabbasi, Ahmad H.
Albuqami, Amjad M.
Hawa, Hassan
author_sort Alharbi, Reham A.
collection PubMed
description BACKGROUND: Percent fluid overload greater than 5% is associated with increased mortality. The appropriate time for fluid deresuscitation depends on the patient's radiological and clinical findings. This study aimed to assess the applicability of percent fluid overload calculations for evaluating the need for fluid deresuscitation in critically ill patients. METHODS: This was a single-center, prospective, observational study of critically ill adult patients requiring intravenous fluid administration. The study's primary outcome was median percent fluid accumulation on the day of fluid deresuscitation or intensive care unit (ICU) discharge, whichever came first. RESULTS: A total of 388 patients was screened between August 1, 2021, and April 30, 2022. Of these, 100 with a mean age of 59.8±16.2 years were included for analysis. The mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 15.4±8.0. Sixty-one patients (61.0%) required fluid deresuscitation during their ICU stay, while 39 (39.0%) did not. Median percent fluid accumulation on the day of deresuscitation or ICU discharge was 4.5% (interquartile range [IQR], 1.7%–9.1%) and 5.2% (IQR, 2.9%–7.7%) in patients requiring deresuscitation and those who did not, respectively. Hospital mortality occurred in 25 (40.9%) of patients with deresuscitation and six (15.3%) patients who did not require it (P=0.007). CONCLUSIONS: The percent fluid accumulation on the day of fluid deresuscitation or ICU discharge was not statistically different between patients who required fluid deresuscitation and those who did not. A larger sample size is needed to confirm these findings.
format Online
Article
Text
id pubmed-10265412
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Korean Society of Critical Care Medicine
record_format MEDLINE/PubMed
spelling pubmed-102654122023-06-15 Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study Alharbi, Reham A. Aldardeer, Namareq F. Heaphy, Emily L. G. Alabbasi, Ahmad H. Albuqami, Amjad M. Hawa, Hassan Acute Crit Care Original Article BACKGROUND: Percent fluid overload greater than 5% is associated with increased mortality. The appropriate time for fluid deresuscitation depends on the patient's radiological and clinical findings. This study aimed to assess the applicability of percent fluid overload calculations for evaluating the need for fluid deresuscitation in critically ill patients. METHODS: This was a single-center, prospective, observational study of critically ill adult patients requiring intravenous fluid administration. The study's primary outcome was median percent fluid accumulation on the day of fluid deresuscitation or intensive care unit (ICU) discharge, whichever came first. RESULTS: A total of 388 patients was screened between August 1, 2021, and April 30, 2022. Of these, 100 with a mean age of 59.8±16.2 years were included for analysis. The mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 15.4±8.0. Sixty-one patients (61.0%) required fluid deresuscitation during their ICU stay, while 39 (39.0%) did not. Median percent fluid accumulation on the day of deresuscitation or ICU discharge was 4.5% (interquartile range [IQR], 1.7%–9.1%) and 5.2% (IQR, 2.9%–7.7%) in patients requiring deresuscitation and those who did not, respectively. Hospital mortality occurred in 25 (40.9%) of patients with deresuscitation and six (15.3%) patients who did not require it (P=0.007). CONCLUSIONS: The percent fluid accumulation on the day of fluid deresuscitation or ICU discharge was not statistically different between patients who required fluid deresuscitation and those who did not. A larger sample size is needed to confirm these findings. Korean Society of Critical Care Medicine 2023-05 2023-05-16 /pmc/articles/PMC10265412/ /pubmed/37313667 http://dx.doi.org/10.4266/acc.2022.01550 Text en Copyright © 2023 The Korean Society of Critical Care Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Alharbi, Reham A.
Aldardeer, Namareq F.
Heaphy, Emily L. G.
Alabbasi, Ahmad H.
Albuqami, Amjad M.
Hawa, Hassan
Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title_full Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title_fullStr Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title_full_unstemmed Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title_short Percent fluid overload for prediction of fluid de-escalation in critically ill patients in Saudi Arabia: a prospective observational study
title_sort percent fluid overload for prediction of fluid de-escalation in critically ill patients in saudi arabia: a prospective observational study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265412/
https://www.ncbi.nlm.nih.gov/pubmed/37313667
http://dx.doi.org/10.4266/acc.2022.01550
work_keys_str_mv AT alharbirehama percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy
AT aldardeernamareqf percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy
AT heaphyemilylg percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy
AT alabbasiahmadh percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy
AT albuqamiamjadm percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy
AT hawahassan percentfluidoverloadforpredictionoffluiddeescalationincriticallyillpatientsinsaudiarabiaaprospectiveobservationalstudy