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Riboswitches, from cognition to transformation
Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265488/ https://www.ncbi.nlm.nih.gov/pubmed/37325181 http://dx.doi.org/10.1016/j.synbio.2023.05.008 |
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author | Xu, Jingdong Hou, Junyuan Ding, Mengnan Wang, Zhiwen Chen, Tao |
author_facet | Xu, Jingdong Hou, Junyuan Ding, Mengnan Wang, Zhiwen Chen, Tao |
author_sort | Xu, Jingdong |
collection | PubMed |
description | Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition of RNA function as well. Here, we focus on some representative orphan riboswitches, enumerate the structural and functional transformation and artificial design of riboswitches including the coupling with ribozymes, hoping to attain a comprehensive understanding of riboswitch research. |
format | Online Article Text |
id | pubmed-10265488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-102654882023-06-15 Riboswitches, from cognition to transformation Xu, Jingdong Hou, Junyuan Ding, Mengnan Wang, Zhiwen Chen, Tao Synth Syst Biotechnol Review Article Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition of RNA function as well. Here, we focus on some representative orphan riboswitches, enumerate the structural and functional transformation and artificial design of riboswitches including the coupling with ribozymes, hoping to attain a comprehensive understanding of riboswitch research. KeAi Publishing 2023-06-03 /pmc/articles/PMC10265488/ /pubmed/37325181 http://dx.doi.org/10.1016/j.synbio.2023.05.008 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Xu, Jingdong Hou, Junyuan Ding, Mengnan Wang, Zhiwen Chen, Tao Riboswitches, from cognition to transformation |
title | Riboswitches, from cognition to transformation |
title_full | Riboswitches, from cognition to transformation |
title_fullStr | Riboswitches, from cognition to transformation |
title_full_unstemmed | Riboswitches, from cognition to transformation |
title_short | Riboswitches, from cognition to transformation |
title_sort | riboswitches, from cognition to transformation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265488/ https://www.ncbi.nlm.nih.gov/pubmed/37325181 http://dx.doi.org/10.1016/j.synbio.2023.05.008 |
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