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Computational Assessment of a Dual-Action Ru(II)-Based Complex: Photosensitizer in Photodynamic Therapy and Intercalating Agent for Inducing DNA Damage

[Image: see text] A combined quantum-mechanical and classical molecular dynamics study of a recent Ru(II) complex with potential dual anticancer action is reported here. The main basis for the multiple action relies on the merocyanine ligand, whose electronic structure allows the drug to be able to...

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Detalles Bibliográficos
Autores principales:	Ponte, Fortuna, Scoditti, Stefano, Barretta, Pierraffaele, Mazzone, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265706/ https://www.ncbi.nlm.nih.gov/pubmed/37248070 http://dx.doi.org/10.1021/acs.inorgchem.3c00592

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