Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness

BACKGROUND: Familial breast cancer is in most cases unexplained due to the lack of identifiable pathogenic variants in the BRCA1 and BRCA2 genes. The somatic mutational landscape and in particular the extent of BRCA-like tumour features (BRCAness) in these familial breast cancers where germline BRCA...

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Detalles Bibliográficos
Autores principales: Andersen, Lars v. B., Larsen, Martin J., Davies, Helen, Degasperi, Andrea, Nielsen, Henriette Roed, Jensen, Louise A., Kroeldrup, Lone, Gerdes, Anne-Marie, Lænkholm, Anne-Vibeke, Kruse, Torben A., Nik-Zainal, Serena, Thomassen, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265777/
https://www.ncbi.nlm.nih.gov/pubmed/37316882
http://dx.doi.org/10.1186/s13058-023-01655-y

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