Cargando…

Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs

One of the key obstacles to malaria elimination is largely attributed to Plasmodium vivax’s ability to form resilient hypnozoites in the host liver that cause relapsing infections. As a result, interruption of P. vivax transmission is difficult. P. vivax transmission occurs in Duffy-positive individ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dembele, Laurent, Diakite, Ousmaila, Sogore, Fanta, Kedir, Soriya, Tandina, Fatalmoudou, Maiga, Mohamed, Abate, Andargie, Golassa, Lemu, Djimde, Abdoulaye A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265784/ https://www.ncbi.nlm.nih.gov/pubmed/37312065 http://dx.doi.org/10.1186/s12879-023-08381-y

Ejemplares similares

Infectivity of Symptomatic Patients and Their Contribution for Infectiousness of Mosquitoes following a Membrane Feeding Assay in Ethiopia
por: Abate, Andargie, et al.
Publicado: (2022)

Ex Vivo Plasmodium malariae Culture Method for Antimalarial Drugs Screen in the Field
por: Dembele, Laurent, et al.
Publicado: (2021)

Differential transmissibility to Anopheles arabiensis of Plasmodium vivax gametocytes in patients with diverse Duffy blood group genotypes
por: Abate, Andargie, et al.
Publicado: (2023)

Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia
por: Abate, Andargie, et al.
Publicado: (2022)

Hypnozoite depletion in successive Plasmodium vivax relapses
por: Noviyanti, Rintis, et al.
Publicado: (2022)

Propensity of selecting mutant parasites for the antimalarial drug cabamiquine
por: Stadler, Eva, et al.
Publicado: (2023)

Comparative Susceptibility of Plasmodium ovale and Plasmodium falciparum Field Isolates to Reference and Lead Candidate Antimalarial Drugs in Ghana
por: Aniweh, Yaw, et al.
Publicado: (2023)

Author Correction: Propensity of selecting mutant parasites for the antimalarial drug cabamiquine
por: Stadler, Eva, et al.
Publicado: (2023)

Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission
por: White, Michael T, et al.
Publicado: (2014)

Sequence analysis of Plasmodium vivax Duffy binding proteins reveals the presence of unique haplotypes and diversifying selection in Ethiopian isolates
por: Golassa, Lemu, et al.
Publicado: (2021)

Modeling the Dynamics of Plasmodium vivax Infection and Hypnozoite Reactivation In Vivo
por: Adekunle, Adeshina I., et al.
Publicado: (2015)

Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework
por: Mehra, Somya, et al.
Publicado: (2023)

Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
por: Flannery, Erika L., et al.
Publicado: (2022)

Activation of the hypnozoite: a part of Plasmodium vivax life cycle and survival
por: Hulden, Lena, et al.
Publicado: (2011)

Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts
por: Sylvester, Kayla, et al.
Publicado: (2021)

A Novel Ex Vivo Drug Assay for Assessing the Transmission-Blocking Activity of Compounds on Field-Isolated Plasmodium falciparum Gametocytes
por: Ouologuem, Dinkorma T., et al.
Publicado: (2022)

Five-Year Trend of Malaria Prevalence in Mojo Town, Central Ethiopia: Shifting Burden of the Disease and Its Implication for Malaria Elimination: A Retrospective Study
por: Abate, Andargie, et al.
Publicado: (2022)

Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence
por: Abebe, Abnet, et al.
Publicado: (2023)

Multiple-Clone Activation of Hypnozoites Is the Leading Cause of Relapse in Plasmodium vivax Infection
por: de Araujo, Flávia Carolina F., et al.
Publicado: (2012)

Antimalarial drug discovery: targeting the hypnozoite for new radical curative agent
por: Yeung, Bryan
Publicado: (2012)

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
por: Maher, S. P., et al.
Publicado: (2023)

Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections
por: Gualdrón-López, Melisa, et al.
Publicado: (2022)

Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts
por: Rodríguez-Hernández, Diego, et al.
Publicado: (2023)

A retrospective analysis on the transmission of Plasmodium falciparum and Plasmodium vivax: the case of Adama City, East Shoa Zone, Oromia, Ethiopia
por: File, Temesgen, et al.
Publicado: (2019)

Polymorphisms in chloroquine resistance-associated genes in Plasmodium vivax in Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2015)

Correction to: Polymorphisms in chloroquine resistance-associated genes in Plasmodium vivax in Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2018)

Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery
por: Dembele, Laurent, et al.
Publicado: (2011)

Tackling malaria transmission at a single cell level in an endemic setting in sub-Saharan Africa
por: Dara, Antoine, et al.
Publicado: (2022)

Population-level estimates of the proportion of Plasmodium vivax blood-stage infections attributable to relapses among febrile patients attending Adama Malaria Diagnostic Centre, East Shoa Zone, Oromia, Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2017)

The biology of unconventional invasion of Duffy-negative reticulocytes by Plasmodium vivax and its implication in malaria epidemiology and public health
por: Golassa, Lemu, et al.
Publicado: (2020)

Liver-stage fate determination in Plasmodium vivax parasites: Characterization of schizont growth and hypnozoite fating from patient isolates
por: Vantaux, Amélie, et al.
Publicado: (2022)

Alternative Invasion Mechanisms and Host Immune Response to Plasmodium vivax Malaria: Trends and Future Directions
por: Kepple, Daniel, et al.
Publicado: (2020)

No more monkeying around: primate malaria model systems are key to understanding Plasmodium vivax liver-stage biology, hypnozoites, and relapses
por: Joyner, Chester, et al.
Publicado: (2015)

How radical is radical cure? Site-specific biases in clinical trials underestimate the effect of radical cure on Plasmodium vivax hypnozoites
por: Huber, John H., et al.
Publicado: (2021)

Significant number of Plasmodium vivax mono-infections by PCR misidentified as mixed infections (P. vivax/P. falciparum) by microscopy and rapid diagnostic tests: malaria diagnostic challenges in Ethiopia
por: Abebe, Abnet, et al.
Publicado: (2023)

Use of MALDI-TOF MS and culturomics to identify mosquitoes and their midgut microbiota
por: Tandina, Fatalmoudou, et al.
Publicado: (2016)

Microscopic and molecular evidence of the presence of asymptomatic Plasmodium falciparum and Plasmodium vivax infections in an area with low, seasonal and unstable malaria transmission in Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2015)

Large differences in variability for genes associated with antimalarial drug resistance between samples from Tanzania and Ethiopia
por: Golassa, Lemu, et al.
Publicado: (2014)

A dual fluorescent Plasmodium cynomolgi reporter line reveals in vitro malaria hypnozoite reactivation
por: Voorberg-van der Wel, Annemarie M., et al.
Publicado: (2020)

The molecular basis of antimalarial drug resistance in Plasmodium vivax
por: Buyon, Lucas E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mpe0a93okpfjcsnkqkrrh65fuu