Osteoarthritic chondrocytes undergo a glycolysis-related metabolic switch upon exposure to IL-1b or TNF

BACKGROUND: Osteoarthritis is an age-related disease that currently faces a lack of symptomatic treatment. Inflammation, which is mainly sustained by pro-inflammatory cytokines such as IL-1b, TNF, and IL-6, plays an important role in osteoarthritis progression. In this context, pro-inflammatory cyto...

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Detalles Bibliográficos
Autores principales: Defois, Anais, Bon, Nina, Charpentier, Alexandre, Georget, Melina, Gaigeard, Nicolas, Blanchard, Frederic, Hamel, Antoine, Waast, Denis, Armengaud, Jean, Renoult, Ophelie, Pecqueur, Claire, Maugars, Yves, Boutet, Marie-Astrid, Guicheux, Jerome, Vinatier, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265918/
https://www.ncbi.nlm.nih.gov/pubmed/37316888
http://dx.doi.org/10.1186/s12964-023-01150-z

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