Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection

The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly evolving viruses. Therefore, durable, effective antibodies must be both broad and potent to counter newly emerging, diverse strains. Discovery of such antibodies is critically important for SARS-CoV-2 as th...

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Detalles Bibliográficos
Autores principales: Guenthoer, Jamie, Lilly, Michelle, Starr, Tyler N., Dadonaite, Bernadeta, Lovendahl, Klaus N., Croft, Jacob T., Stoddard, Caitlin I., Chohan, Vrasha, Ding, Shilei, Ruiz, Felicitas, Kopp, Mackenzie S., Finzi, Andrés, Bloom, Jesse D., Chu, Helen Y., Lee, Kelly K., Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265947/
https://www.ncbi.nlm.nih.gov/pubmed/37253011
http://dx.doi.org/10.1073/pnas.2220948120

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