Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape

Succinate produced by the commensal protist Tritrichomonas musculis (T. mu) stimulates chemosensory tuft cells, resulting in intestinal type 2 immunity. Tuft cells express the succinate receptor SUCNR1, yet this receptor does not mediate antihelminth immunity nor alter protist colonization. Here, we...

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Detalles Bibliográficos
Autores principales: Fung, Connie, Fraser, Lisa M., Barrón, Gabriel M., Gologorsky, Matthew B., Atkinson, Samantha N., Gerrick, Elias R., Hayward, Michael, Ziegelbauer, Jennifer, Li, Jessica A., Nico, Katherine F., Tyner, Miles D. W., DeSchepper, Leila B., Pan, Amy, Salzman, Nita H., Howitt, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266004/
https://www.ncbi.nlm.nih.gov/pubmed/37253002
http://dx.doi.org/10.1073/pnas.2216908120

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