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Succinyl-CoA ligase ADP-forming subunit beta promotes stress granule assembly to regulate redox and drive cancer metastasis

Although recent studies demonstrate active mitochondrial metabolism in cancers, the precise mechanisms through which mitochondrial factors contribute to cancer metastasis remain elusive. Through a customized mitochondrion RNAi screen, we identified succinyl-CoA ligase ADP-forming subunit beta (SUCLA...

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Detalles Bibliográficos
Autores principales: Boese, Austin C., Kang, JiHoon, Hwang, Jung Seok, Kim, Jaehyun, Eun, Kiyoung, Malin, Courteney M., Magliocca, Kelly R., Pan, Chaoyun, Jin, Lingtao, Kang, Sumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266061/
https://www.ncbi.nlm.nih.gov/pubmed/37253003
http://dx.doi.org/10.1073/pnas.2217332120