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Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice
Positively selected germinal center B cells (GCBC) can either resume proliferation and somatic hypermutation or differentiate. The mechanisms dictating these alternative cell fates are incompletely understood. We show that the protein arginine methyltransferase 1 (Prmt1) is upregulated in murine GCB...
Autores principales: | Litzler, Ludivine C., Zahn, Astrid, Dionne, Kiersten L., Sprumont, Adrien, Ferreira, Silvana R., Slattery, Michael R.F., Methot, Stephen P., Patenaude, Anne-Marie, Hébert, Steven, Kabir, Nisha, Subramani, Poorani Ganesh, Jung, Seolkyoung, Richard, Stéphane, Kleinman, Claudia L., Di Noia, Javier M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266067/ https://www.ncbi.nlm.nih.gov/pubmed/37310381 http://dx.doi.org/10.1084/jem.20220381 |
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