Induction of Immune Responses and Phosphatidylserine Exposure by TLR9 Activation Results in a Cooperative Antitumor Effect with a Phosphatidylserine-targeting Prodrug

Head and neck cancer is a major cancer type, with high motility rates that reduce the quality of life of patients. Herein, we investigated the effectiveness and mechanism of a combination therapy involving TLR9 activator (CpG-2722) and phosphatidylserine (PS)-targeting prodrug of SN38 (BPRDP056) in...

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Detalles Bibliográficos
Autores principales: Tseng, Jen-Chih, Yang, Jing-Xing, Lee, Chia-Yin, Lo, Chen-Fu, Liu, Yi-Ling, Zhang, Mingzi M., Huang, Li-Rung, Liu, Ko-Jiunn, Wang, Chien-Chia, Huang, Chi-Ying F., Hong, Yi-Ren, Tsou, Lun K., Chuang, Tsung-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266080/
https://www.ncbi.nlm.nih.gov/pubmed/37324949
http://dx.doi.org/10.7150/ijbs.81683

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