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Ability of Local Clearance of Senescent Cells in Ipsilateral Hemisphere to Mitigate Acute Ischemic Brain Injury in Mice

Senolytic treatment has potential therapeutic efficacy for acute ischemic stroke (AIS). However, the systemic treatment of senolytics may produce off-target side effects and a toxic profile, which affect analysis of the role of acute senescence of neuronal cells in pathogenesis of AIS. We constructe...

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Detalles Bibliográficos
Autores principales: Lu, Kuan-Jung, Sheu, Joen-Rong, Teng, Ruei-Dun, Jayakumar, Tanasekar, Chung, Chi-Li, Hsieh, Cheng-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266088/
https://www.ncbi.nlm.nih.gov/pubmed/37324944
http://dx.doi.org/10.7150/ijbs.84060