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Negatively charged phospholipids doped liposome delivery system for mRNA with high transfection efficiency and low cytotoxicity

Messenger RNA (mRNA) has become one of the most potential drugs in recent years. However, efficient and safe delivery of fragile and easily degradable mRNA is a major challenge. Appropriate delivery system (DS) determines the final effect of mRNA. Cationic lipids play a crucial and decisive role in...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Xing, Huanchun, Guo, Shuai, Cao, Wenbin, Zhang, Zinan, Huang, Lijuan, Xin, Sui, Luo, Yuan, Wang, Yongan, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266121/
https://www.ncbi.nlm.nih.gov/pubmed/37309122
http://dx.doi.org/10.1080/10717544.2023.2219869