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Negatively charged phospholipids doped liposome delivery system for mRNA with high transfection efficiency and low cytotoxicity
Messenger RNA (mRNA) has become one of the most potential drugs in recent years. However, efficient and safe delivery of fragile and easily degradable mRNA is a major challenge. Appropriate delivery system (DS) determines the final effect of mRNA. Cationic lipids play a crucial and decisive role in...
Autores principales: | Wang, Lin, Xing, Huanchun, Guo, Shuai, Cao, Wenbin, Zhang, Zinan, Huang, Lijuan, Xin, Sui, Luo, Yuan, Wang, Yongan, Yang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266121/ https://www.ncbi.nlm.nih.gov/pubmed/37309122 http://dx.doi.org/10.1080/10717544.2023.2219869 |
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