AhR agonist tapinarof ameliorates lupus autoimmunity by suppressing Tfh cell differentiation via regulation of the JAK2‐STAT3 signaling pathway

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a critical regulator of the pathogenesis of autoimmune disorders. We aimed to investigate the therapeutic effect of the AhR agonist tapinarof during the development of systemic lupus erythematosus (SLE). METHODS: MRL/lpr mice were intraperitoneally...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Pan, Yanyan, Zhang, Peiyi, Wang, Fang, Han, Ying, Li, Kailin, Jiang, Wen, Wang, Jue, Luan, Yun, Xin, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266146/
https://www.ncbi.nlm.nih.gov/pubmed/37382269
http://dx.doi.org/10.1002/iid3.903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266146/
https://www.ncbi.nlm.nih.gov/pubmed/37382269
http://dx.doi.org/10.1002/iid3.903

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