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Viral infection reveals hidden sharing of TCR CDR3 sequences between individuals

The T cell receptor is generated by a process of random and imprecise somatic recombination. The number of possible T cell receptors which this process can produce is enormous, greatly exceeding the number of T cells in an individual. Thus, the likelihood of identical TCRs being observed in multiple...

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Detalles Bibliográficos
Autores principales:	Mark, Michal, Reich-Zeliger, Shlomit, Greenstein, Erez, Biram, Adi, Chain, Benny, Friedman, Nir, Madi, Asaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266217/ https://www.ncbi.nlm.nih.gov/pubmed/37325645 http://dx.doi.org/10.3389/fimmu.2023.1199064

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