Proline-rich acidic protein 1 upregulates mitotic arrest deficient 1 to promote cisplatin-resistance of colorectal carcinoma by restraining mitotic checkpoint complex assembly

Background: The mechanism underlying cisplatin resistance in colorectal carcinoma (CRC) has not yet been elucidated. This study is aimed to illustrate the indispensable role of proline-rich acidic protein 1 (PRAP1) in cisplatin-resistant CRC. Methods: Cell viability and apoptosis were monitored usin...

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Detalles Bibliográficos
Autores principales: Song, Jintian, Chen, Yigui, Yu, Hui, Zheng, Liang, Wang, Yi, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266255/
https://www.ncbi.nlm.nih.gov/pubmed/37325046
http://dx.doi.org/10.7150/jca.84048

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