Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India

This study investigated the major pathogens in fever patients’ blood in a rural cohort and characterized its virulence. A total of 718 blood samples received from IPD/OPD (inpatient department/outpatient department) patients with H/O (history of) fever were cultured, and 73 out of 83 culture-positiv...

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Autores principales: Dash, Pujarini, Rana, Khokan, Turuk, Jyotirmayee, Palo, Subrata Kumar, Pati, Sanghamitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266288/
https://www.ncbi.nlm.nih.gov/pubmed/37013928
http://dx.doi.org/10.33073/pjm-2023-005
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author Dash, Pujarini
Rana, Khokan
Turuk, Jyotirmayee
Palo, Subrata Kumar
Pati, Sanghamitra
author_facet Dash, Pujarini
Rana, Khokan
Turuk, Jyotirmayee
Palo, Subrata Kumar
Pati, Sanghamitra
author_sort Dash, Pujarini
collection PubMed
description This study investigated the major pathogens in fever patients’ blood in a rural cohort and characterized its virulence. A total of 718 blood samples received from IPD/OPD (inpatient department/outpatient department) patients with H/O (history of) fever were cultured, and 73 out of 83 culture-positive samples were identified as Staphylococcus aureus. The isolates showed higher resistance to penicillin, most being multidrug resistant. They formed biofilm in vitro, and 27.4% of the isolates were strong biofilm producers. They were sensitive towards linezolid, gentamicin, and tetracycline. The findings emphasize the necessity of preventing and managing staphylococcal infection and regular antimicrobial surveillance in rural areas.
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spelling pubmed-102662882023-06-15 Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India Dash, Pujarini Rana, Khokan Turuk, Jyotirmayee Palo, Subrata Kumar Pati, Sanghamitra Pol J Microbiol Short Communication This study investigated the major pathogens in fever patients’ blood in a rural cohort and characterized its virulence. A total of 718 blood samples received from IPD/OPD (inpatient department/outpatient department) patients with H/O (history of) fever were cultured, and 73 out of 83 culture-positive samples were identified as Staphylococcus aureus. The isolates showed higher resistance to penicillin, most being multidrug resistant. They formed biofilm in vitro, and 27.4% of the isolates were strong biofilm producers. They were sensitive towards linezolid, gentamicin, and tetracycline. The findings emphasize the necessity of preventing and managing staphylococcal infection and regular antimicrobial surveillance in rural areas. Sciendo 2023-06-14 /pmc/articles/PMC10266288/ /pubmed/37013928 http://dx.doi.org/10.33073/pjm-2023-005 Text en © 2023 Pujarini Dash et al., published by Sciendo https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Short Communication
Dash, Pujarini
Rana, Khokan
Turuk, Jyotirmayee
Palo, Subrata Kumar
Pati, Sanghamitra
Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title_full Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title_fullStr Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title_full_unstemmed Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title_short Antimicrobial Resistance and Biofilm Formation of Staphylococcus aureus Isolates from Febrile Cases: Findings from a Rural Cohort of Odisha, India
title_sort antimicrobial resistance and biofilm formation of staphylococcus aureus isolates from febrile cases: findings from a rural cohort of odisha, india
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266288/
https://www.ncbi.nlm.nih.gov/pubmed/37013928
http://dx.doi.org/10.33073/pjm-2023-005
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