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Afatinib combined with anti-PD1 enhances immunotherapy of hepatocellular carcinoma via ERBB2/STAT3/PD-L1 signaling

BACKGROUND: Afatinib is mainly used to treat advanced non-small cell lung cancer, but its therapeutic effect on hepatocellular carcinoma is still unclear. METHODS: Over 800 drugs were screened by CCK8 technology and afatinib was found to have a significant inhibitory effect on liver cancer cells. Th...

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Detalles Bibliográficos
Autores principales:	Yu, Chao, Zhang, Xinyi, Wang, Min, Xu, Gaoxin, Zhao, Siqi, Feng, Yongheng, Pan, Chao, Yang, Weijun, Zhou, Jin, Shang, Longcheng, Ma, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266343/ https://www.ncbi.nlm.nih.gov/pubmed/37324014 http://dx.doi.org/10.3389/fonc.2023.1198118

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