Cargando…
Case Report: An unclassified T cell lymphoma subtype with co-expression of TCR αβ and γ chains revealed by single cell sequencing
BACKGROUND: T cell lymphomas (TCL) are a group of heterogeneous diseases with over 40 subtypes. In this study, we identified a novel TCL subtype which was featured by a unique T cell receptor (TCR) presentation, α, β and γ chains were co-existing in a single malignant T cell. CASE PRESENTATION: A 45...
Autores principales: | Song, Wei, Wang, Gang, Wang, Cheng, Liu, Lulu, Zhang, Liming, Zhang, Ruoyu, Zhang, Haixi, Shi, Keqian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266344/ https://www.ncbi.nlm.nih.gov/pubmed/37325644 http://dx.doi.org/10.3389/fimmu.2023.1184383 |
Ejemplares similares
-
Revisiting the Discovery of the αβ TCR Complex and Its Co-Receptors
por: Reinherz, Ellis L.
Publicado: (2014) -
Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progression
por: Song, Wei, et al.
Publicado: (2022) -
Identification and Regulation of TCRαβ(+)CD8αα(+) Intraepithelial Lymphocytes in Murine Oral Mucosa
por: Wu, Ruiqing, et al.
Publicado: (2020) -
Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination
por: Brazin, Kristine N., et al.
Publicado: (2015) -
Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity
por: Carter, Jason A., et al.
Publicado: (2019)