Long non-coding RNA lncMGC mediates the expression of TGF-β-induced genes in renal cells via nucleosome remodelers

Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play key roles in diabetic kidney disease (DKD). The miR-379 megacluster of miRNAs and its host transcript lnc-megacluster (lncMGC) are regulated by transforming growth factor-β (TGF-β), increased in the glomeruli of diabetic mice, an...

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Detalles Bibliográficos
Autores principales: Kato, Mitsuo, Chen, Zhuo, Das, Sadhan, Wu, Xiwei, Wang, Jinhui, Li, Arthur, Chen, Wei, Tsark, Walter, Tunduguru, Ragadeepthi, Lanting, Linda, Wang, Mei, Moore, Roger, Kalkum, Markus, Abdollahi, Maryam, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266347/
https://www.ncbi.nlm.nih.gov/pubmed/37325470
http://dx.doi.org/10.3389/fmolb.2023.1204124

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