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Rise of the RNA machines – self-amplification in mRNA vaccine design
mRNA vaccines have won the race for early COVID-19 vaccine approval, yet improvements are necessary to retain this leading role in combating infectious diseases. A next generation of self-amplifying mRNAs, also known as replicons, form an ideal vaccine platform. Replicons induce potent humoral and c...
Autores principales: | Comes, Jerome D.G., Pijlman, Gorben P., Hick, Tessy A.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266560/ https://www.ncbi.nlm.nih.gov/pubmed/37328401 http://dx.doi.org/10.1016/j.tibtech.2023.05.007 |
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