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Rise of the RNA machines – self-amplification in mRNA vaccine design

mRNA vaccines have won the race for early COVID-19 vaccine approval, yet improvements are necessary to retain this leading role in combating infectious diseases. A next generation of self-amplifying mRNAs, also known as replicons, form an ideal vaccine platform. Replicons induce potent humoral and c...

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Detalles Bibliográficos
Autores principales: Comes, Jerome D.G., Pijlman, Gorben P., Hick, Tessy A.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266560/
https://www.ncbi.nlm.nih.gov/pubmed/37328401
http://dx.doi.org/10.1016/j.tibtech.2023.05.007

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