Evaluation of (18)F labeled glial fibrillary acidic protein binding nanobody and its brain shuttle peptide fusion proteins using a neuroinflammation rat model

Astrogliosis is a crucial feature of neuroinflammation and is characterized by the significant upregulation of glial fibrillary acidic protein (GFAP) expression. Hence, visualizing GFAP in the living brain of patients with damaged central nervous system using positron emission tomography (PET) is of...

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Detalles Bibliográficos
Autores principales: Morito, Takahiro, Harada, Ryuichi, Iwata, Ren, Ishikawa, Yoichi, Okamura, Nobuyuki, Kudo, Yukitsuka, Furumoto, Shozo, Yanai, Kazuhiko, Tashiro, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266665/
https://www.ncbi.nlm.nih.gov/pubmed/37315033
http://dx.doi.org/10.1371/journal.pone.0287047

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