CD62L expression marks SARS-CoV-2 memory B cell subset with preference for neutralizing epitopes

Severe acute respiratory syndrome coronavirus 2–neutralizing antibodies primarily target the spike receptor binding domain (RBD). However, B cell antigen receptors (BCRs) on RBD-binding memory B (B(mem)) cells have variation in the neutralizing activities. Here, by combining single B(mem) cell profi...

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Detalles Bibliográficos
Autores principales: Onodera, Taishi, Sax, Nicolas, Sato, Takashi, Adachi, Yu, Kotaki, Ryutaro, Inoue, Takeshi, Shinnakasu, Ryo, Nakagawa, Takayuki, Fukushi, Shuetsu, Terooatea, Tommy, Yoshikawa, Mai, Tonouchi, Keisuke, Nagakura, Takaki, Moriyama, Saya, Matsumura, Takayuki, Isogawa, Masanori, Terahara, Kazutaka, Takano, Tomohiro, Sun, Lin, Nishiyama, Ayae, Omoto, Shinnya, Shinkai, Masaharu, Kurosaki, Tomohiro, Yamashita, Kazuo, Takahashi, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266721/
https://www.ncbi.nlm.nih.gov/pubmed/37315144
http://dx.doi.org/10.1126/sciadv.adf0661

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