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Rapid protein stability prediction using deep learning representations

Predicting the thermodynamic stability of proteins is a common and widely used step in protein engineering, and when elucidating the molecular mechanisms behind evolution and disease. Here, we present RaSP, a method for making rapid and accurate predictions of changes in protein stability by leverag...

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Detalles Bibliográficos
Autores principales: Blaabjerg, Lasse M, Kassem, Maher M, Good, Lydia L, Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer E, Boomsma, Wouter, Stein, Amelie, Lindorff-Larsen, Kresten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266766/
https://www.ncbi.nlm.nih.gov/pubmed/37184062
http://dx.doi.org/10.7554/eLife.82593

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