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KIR-HLA interactions extend human CD8(+) T cell lifespan in vivo

BACKGROUND: There is increasing evidence, in transgenic mice and in vitro, that inhibitory killer cell immunoglobulin-like receptors (iKIRs) can modulate T cell responses. Furthermore, we have previously shown that iKIRs are an important determinant of T cell–mediated control of chronic viral infect...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Yan, Ada W.C., Boelen, Lies, Hadcocks, Linda, Salam, Arafa, Gispert, Daniel Padrosa, Spanos, Loiza, Bitria, Laura Mora, Nemat-Gorgani, Neda, Traherne, James A., Roberts, Chrissy, Koftori, Danai, Taylor, Graham P., Forton, Daniel, Norman, Paul J., Marsh, Steven G.E., Busch, Robert, Macallan, Derek C., Asquith, Becca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2023
Materias:	Clinical Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266773/ https://www.ncbi.nlm.nih.gov/pubmed/37071474 http://dx.doi.org/10.1172/JCI169496

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