Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia

Ras plays an essential role in the development of acinar-to-ductal metaplasia (ADM) and pancreatic ductal adenocarcinoma (PDAC). However, mutant Kras is an inefficient driver for PDAC development. The mechanisms of the switching from low Ras activity to high Ras activity that are required for develo...

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Detalles Bibliográficos
Autores principales: Wang, Hua, Moniruzzaman, Rohan, Li, Lei, Ji, Baoan, Liu, Yi, Zuo, Xiangsheng, Abbasgholizadeh, Reza, Zhao, Jun, Liu, Guangchao, Wang, Ruiqi, Tang, Hongli, Sun, Ryan, Su, Xiaoping, Tan, Tse-Hua, Maitra, Anirban, Wang, Huamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266776/
https://www.ncbi.nlm.nih.gov/pubmed/37140994
http://dx.doi.org/10.1172/JCI163873

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