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Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy

Brain microglia (MG) may serve as a human immunodeficiency virus 1 (HIV) reservoir and ignite rebound viremia following cessation of antiretroviral therapy (ART), but they have yet to be proven to harbor replication-competent HIV. Here, we isolated brain myeloid cells (BrMCs) from nonhuman primates...

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Detalles Bibliográficos
Autores principales: Tang, Yuyang, Chaillon, Antoine, Gianella, Sara, Wong, Lilly M., Li, Dajiang, Simermeyer, Theresa L., Porrachia, Magali, Ignacio, Caroline, Woodworth, Brendon, Zhong, Daniel, Du, Jiayi, de la Parra Polina, Eduardo, Kirchherr, Jennifer, Allard, Brigitte, Clohosey, Matthew L., Moeser, Matt, Sondgeroth, Amy L., Whitehill, Gregory D., Singh, Vidisha, Dashti, Amir, Smith, Davey M., Eron, Joseph J., Bar, Katherine J., Chahroudi, Ann, Joseph, Sarah B., Archin, Nancie M., Margolis, David M., Jiang, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266791/
https://www.ncbi.nlm.nih.gov/pubmed/37317962
http://dx.doi.org/10.1172/JCI167417

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