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Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy
Brain microglia (MG) may serve as a human immunodeficiency virus 1 (HIV) reservoir and ignite rebound viremia following cessation of antiretroviral therapy (ART), but they have yet to be proven to harbor replication-competent HIV. Here, we isolated brain myeloid cells (BrMCs) from nonhuman primates...
Autores principales: | Tang, Yuyang, Chaillon, Antoine, Gianella, Sara, Wong, Lilly M., Li, Dajiang, Simermeyer, Theresa L., Porrachia, Magali, Ignacio, Caroline, Woodworth, Brendon, Zhong, Daniel, Du, Jiayi, de la Parra Polina, Eduardo, Kirchherr, Jennifer, Allard, Brigitte, Clohosey, Matthew L., Moeser, Matt, Sondgeroth, Amy L., Whitehill, Gregory D., Singh, Vidisha, Dashti, Amir, Smith, Davey M., Eron, Joseph J., Bar, Katherine J., Chahroudi, Ann, Joseph, Sarah B., Archin, Nancie M., Margolis, David M., Jiang, Guochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266791/ https://www.ncbi.nlm.nih.gov/pubmed/37317962 http://dx.doi.org/10.1172/JCI167417 |
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