Poly(ADP-ribose) polymerase 9 mediates early protection against Mycobacterium tuberculosis infection by regulating type I IFN production

The ADP ribosyltransferases (PARPs 1–17) regulate diverse cellular processes, including DNA damage repair. PARPs are classified on the basis of their ability to catalyze poly-ADP-ribosylation (PARylation) or mono-ADP-ribosylation (MARylation). Although PARP9 mRNA expression is significantly increase...

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Detalles Bibliográficos
Autores principales: Thirunavukkarasu, Shyamala, Ahmed, Mushtaq, Rosa, Bruce A., Boothby, Mark, Cho, Sung Hoon, Rangel-Moreno, Javier, Mbandi, Stanley K., Schreiber, Valérie, Gupta, Ananya, Zuniga, Joaquin, Mitreva, Makedonka, Kaushal, Deepak, Scriba, Thomas J., Khader, Shabaana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266794/
https://www.ncbi.nlm.nih.gov/pubmed/37200107
http://dx.doi.org/10.1172/JCI158630

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