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Etiology, effects and management of comorbidities in multiple sclerosis: recent advances
Comorbid conditions commonly affect people with multiple sclerosis (MS). Population-based studies indicate that people with MS have an increased incidence of ischemic heart disease, cerebrovascular disease, peripheral vascular disease, and psychiatric disorders as compared to people without MS. Peop...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266935/ https://www.ncbi.nlm.nih.gov/pubmed/37325663 http://dx.doi.org/10.3389/fimmu.2023.1197195 |
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author | Marrie, Ruth Ann Fisk, John D. Fitzgerald, Kathryn Kowalec, Kaarina Maxwell, Colleen Rotstein, Dalia Salter, Amber Tremlett, Helen |
author_facet | Marrie, Ruth Ann Fisk, John D. Fitzgerald, Kathryn Kowalec, Kaarina Maxwell, Colleen Rotstein, Dalia Salter, Amber Tremlett, Helen |
author_sort | Marrie, Ruth Ann |
collection | PubMed |
description | Comorbid conditions commonly affect people with multiple sclerosis (MS). Population-based studies indicate that people with MS have an increased incidence of ischemic heart disease, cerebrovascular disease, peripheral vascular disease, and psychiatric disorders as compared to people without MS. People with MS from underrepresented minority and immigrant groups have higher comorbidity burdens. Comorbidities exert effects throughout the disease course, from symptom onset through diagnosis to the end of life. At the individual level, comorbidity is associated with higher relapse rates, greater physical and cognitive impairments, lower health-related quality of life, and increased mortality. At the level of the health system and society, comorbidity is associated with increased health care utilization, costs and work impairment. A nascent literature suggests that MS affects outcomes from comorbidities. Comorbidity management needs to be integrated into MS care, and this would be facilitated by determining optimal models of care. |
format | Online Article Text |
id | pubmed-10266935 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102669352023-06-15 Etiology, effects and management of comorbidities in multiple sclerosis: recent advances Marrie, Ruth Ann Fisk, John D. Fitzgerald, Kathryn Kowalec, Kaarina Maxwell, Colleen Rotstein, Dalia Salter, Amber Tremlett, Helen Front Immunol Immunology Comorbid conditions commonly affect people with multiple sclerosis (MS). Population-based studies indicate that people with MS have an increased incidence of ischemic heart disease, cerebrovascular disease, peripheral vascular disease, and psychiatric disorders as compared to people without MS. People with MS from underrepresented minority and immigrant groups have higher comorbidity burdens. Comorbidities exert effects throughout the disease course, from symptom onset through diagnosis to the end of life. At the individual level, comorbidity is associated with higher relapse rates, greater physical and cognitive impairments, lower health-related quality of life, and increased mortality. At the level of the health system and society, comorbidity is associated with increased health care utilization, costs and work impairment. A nascent literature suggests that MS affects outcomes from comorbidities. Comorbidity management needs to be integrated into MS care, and this would be facilitated by determining optimal models of care. Frontiers Media S.A. 2023-05-30 /pmc/articles/PMC10266935/ /pubmed/37325663 http://dx.doi.org/10.3389/fimmu.2023.1197195 Text en Copyright © 2023 Marrie, Fisk, Fitzgerald, Kowalec, Maxwell, Rotstein, Salter and Tremlett https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Immunology Marrie, Ruth Ann Fisk, John D. Fitzgerald, Kathryn Kowalec, Kaarina Maxwell, Colleen Rotstein, Dalia Salter, Amber Tremlett, Helen Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title | Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title_full | Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title_fullStr | Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title_full_unstemmed | Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title_short | Etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
title_sort | etiology, effects and management of comorbidities in multiple sclerosis: recent advances |
topic | Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266935/ https://www.ncbi.nlm.nih.gov/pubmed/37325663 http://dx.doi.org/10.3389/fimmu.2023.1197195 |
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