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An antioxidant ameliorates allergic airway inflammation by inhibiting HDAC 1 via HIF-1α/VEGF axis suppression in mice

Histone deacetylase inhibitors (HDACi) are novel class of drugs as they are involved in post translational modification of several proteins involved in signaling pathways related to asthma. HDACi have been reported to elicit protective effects on asthma but the signaling pathways associated with it...

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Detalles Bibliográficos
Autores principales: Islam, Ramiya, Dash, D., Singh, Rashmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267105/
https://www.ncbi.nlm.nih.gov/pubmed/37316684
http://dx.doi.org/10.1038/s41598-023-36678-0