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A mutation-induced drug resistance database (MdrDB)
Mutation-induced drug resistance is a significant challenge to the clinical treatment of many diseases, as structural changes in proteins can diminish drug efficacy. Understanding how mutations affect protein-ligand binding affinities is crucial for developing new drugs and therapies. However, the l...
Autores principales: | Yang, Ziyi, Ye, Zhaofeng, Qiu, Jiezhong, Feng, Rongjun, Li, Danyu, Hsieh, Changyu, Allcock, Jonathan, Zhang, Shengyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267113/ https://www.ncbi.nlm.nih.gov/pubmed/37316673 http://dx.doi.org/10.1038/s42004-023-00920-7 |
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