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A mutation-induced drug resistance database (MdrDB)

Mutation-induced drug resistance is a significant challenge to the clinical treatment of many diseases, as structural changes in proteins can diminish drug efficacy. Understanding how mutations affect protein-ligand binding affinities is crucial for developing new drugs and therapies. However, the l...

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Detalles Bibliográficos
Autores principales: Yang, Ziyi, Ye, Zhaofeng, Qiu, Jiezhong, Feng, Rongjun, Li, Danyu, Hsieh, Changyu, Allcock, Jonathan, Zhang, Shengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267113/
https://www.ncbi.nlm.nih.gov/pubmed/37316673
http://dx.doi.org/10.1038/s42004-023-00920-7

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